SpannerPlantLogo140Cambridge website for Synthetic Biology resources
 
 Compiled by Jim Haseloff at the University of Cambridge
This site contains details of recent papers and activity in Synthetic Biology, with particular emphasis on: (i) development of standards in biology and DNA parts, (ii) microbial and (iii) plant systems, (iv) research and teaching in the field at the University of Cambridge, (v) hardware for scientific computing and instrumentation, (vi) tools for scientific productivity and collected miscellany. 
 
Similar to the Cambridge-based Raspberry Pi and OpenLabTools initiatives, we promote the use of low cost and open source tools - in our case for use in biological engineering.
 

SynBio calendar

  • 21 May
    05:00 AM to 05:00 AM

    This meeting will introduce and showcase the many and varied applications of synthetic biology at the molecular, cell, and whole plant level to introduce synthetic biology to a broad UK plant science base.

  • 29 May

    With their provenance as an excellent source of pharmaceutical, neutraceutical and health promoting chemistries, plant natural products are an attractive target for biotechnological development for industrialization

  • 09 Jun
    12:00 AM to 12:00 AM

    (Re-)constructing and Re-programming Life This conference will provide an in-depth discussion forum among practitioners of the various fields underlying Synthetic Biology. It aims to pin-point the challenges,

  • 10 Jun
    12:00 AM to 12:00 AM

    Algae Innovation Center (AIC) Lolland commenced in 2010 as a project between Green Center, Roskilde University and Aalborg University with the aim of identifying and researching the potentials of using

  • 16 Jun
    12:00 AM to 12:00 AM

    The conference will focus on frontiers in biological design, synthetic biology and processing, bringing together the top academic, industrial and governmental researchers from both the East and the West. Specific

  • 23 Jun
    12:00 AM to 12:00 AM

    A hands-on Summer Course of advanced Genetic Engineering of Bacteria at the onset of the SynBio era.

  • 25 Jun
    12:00 AM to 12:00 AM

    GCAT-alog is freezer management software, optimized for use by synthetic biologists. GCAT-alog is freely available to use though no support other than the user manual is available.The tools can be accessed

  • 29 Jun
    12:00 AM to 12:00 AM

    This week-long summer school provides advanced training in history of the life sciences, a lively international field that offers a long-term perspective on some of the most significant ideas, practices

  • 09 Jul
    12:00 AM to 12:00 AM

    The BioBricks Foundation is pleased to announce The BioBricks Foundation Synthetic Biology 6.0 Conference (SB6.0), which will take place on July 9-11, 2013 at Imperial College, London, UK. This meeting

  • 10 Jul

    SynBioBeta is a forum to bring together synthetic biology startups as well as other stakeholders in the ecosystem. This evening event will be held during the BioBricks Foundation SB6.0 Conference. The

21 May - 30 May
09 Jun - 12 Jun
16 Jun - 07 Jul
25 Jun - 07 Jul
09 Jul - 11 Jul

SynBio Google newsfeed

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Motivation and Synthetic Biology

If you have a spare few minutes, sample the embedded video, which contains an animated view of the nature of human motivation, and the role that it plays in getting stuff done in organisations - from Dan Pink (http://www.danpink.com). Pink's views are especially relevant to Synthetic Biology, where bottom-up organisation, self-motivated efforts and open source technologies are so prominent, compared to the conventional biotechnology field. The animation is great - by RSAnimation (http://comment.rsablogs.org.uk/videos/) after a presentation at the Royal Society for Encouragement of Arts Manufactures and Commerce, London.

Android meets Arduino

BanziAndroid2011

Google has release a package for development of Android phone and tablet apps using Arduino hardware. See a presentation by Massimo Banzi (Arduino) at the Android Open 2011 conference here. The combination of open source hardware platforms offers many opportunities for development of low-cost scientific instruments.

http://arduino.cc/blog/2011/10/12/android-open-2011-massimo-banzi-arduino-android-infinite-possibilities/

Tenure track position in Plant Sciences at Cambridge

Applications are invited for the post of University Lecturer in Plant Sciences. A £250,000 grant from the Gatsby Charitable Foundation is available to support the candidate’s research programme. The appointee will play a central role in the Department's undergraduate teaching. However, the first priority will be to establish a productive research programme and initially the appointee will have only minimal teaching responsibility. There is particular interest in candidates withexpertise the following areas:

Microbiology of viruses, bacteria, fungi or algae, with links either to industrial biotechnology or plant pathology.
Mathematical and computational biology including epidemiology, bioinformatics and complex systems modelling at any level from the cell to the ecosystem.
Ecology and evolution including molecular ecology.
Synthetic biology.
Genome biology of plants, including crops.
Plant Taxonomy


Further particulars are available on http://www.plantsci.cam.ac.uk/jobs/PD09392.pdf

SynBio in The Scientist

Tinkering With Life 

A decade’s worth of engineering-infused biology
In the late 1990s, a handful of physicists and engineers began to take a greater interest in biology. The Human Genome Project was spitting out more and more gene sequences, but no one knew how all these genes and proteins worked together to create a living, breathing organism. . . .
By Jef Akst (New Scientist)

Synthetic Biology video, Bridge8

Bridge8

A great video summary of Synthetic Biology - what it is, and where it might go - from James Hutson at Bridge8 in Australia. (and a brilliant example of how to make an informational video).

From selective breeding to genetic modification, our understanding of biology is now merging with the principles of engineering to bring us synthetic biology.

Written, animated and directed by James Hutson, Bridge8.

http://youtu.be/rD5uNAMbDaQ

iGEM2011 Cambridge: Bactiridescence

New BioBricks for iridescent biosensors and colour from the Cambridge iGEM2011 team. 

RainbowReflectin275The Cambridge iGEM2011 team worked with bionanophotonic systems - experimenting with the use of reflectin proteins from squid, that can assemble into photonic structures with striking iridescence. 

They produced BioBrick compatible forms of reflectin, expressed and purified the proteins, and produced thin films with bright and dynamic reflectance properties (see right). The films responded in fractions of a second to physical changes, such as humidity-induced film swelling. Reflectin colours can be rapidly altered by changes in phosphorylation state in squido. 

 Reflectins form a new class of genetic markers and biosensors with radically improved properties and huge potential.

The team also produced improved software for Gibson Assembly, with an interface to sequence libraries (including the iGEM Registry), graphical construction tool and automated PDF output of oligo design and experimental protocol.

For more information see: http://2011.igem.org/Team:Cambridge

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