Engineering tools for Gram positive bacteria
Gram positive bacteria like Bacillus subtilis provide a number of benefits for synthetic biologists. B. subtilis is non-tranformable and naturally transformable, with an efficient system for homologous transformation. Gram positive bacteria provide the bulk of industrially important species and their architectures allow high level secretion of enzymes and other proteins. The Synthetic Biology group at the University of Cambridge is developing tools for work with B. subtilis. The pages in this section provide access to recent papers and relevant websites in the field.
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Microbes May Be More Networked Than You Are
When we think of networks, we think of humans and the cables we’ve run around the world to connect our species. Figuring out how to move electrons has transformed human society, but we are not the only species on earth that lives in a wired world.
From the Fields is a periodic Wired Science op-ed series presenting leading...
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The bacterial zoo living on your skin
Category: Bacteria • Medicine & health
http://scienceblogs.com/notrocketscience/2009/05/the_bacterial_zoo_living_on_your_skin.php, by Ed Yong
It's a diverse melting-pot of different groups, with hundreds of different cultures living together in harmony, many sticking to their own preferred areas. No, not London, New York or any other...
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Bacteria And Algae Act As Biocatalysts for Deep-sea Raw Material Deposition
ScienceDaily (June 4, 2009) — The sea floor is strewn with raw materials that could be very important in the future: Manganese and iron, but also rarer and more precious elements such as cobalt, copper, zinc and nickel, are present in great quantities in the form of deep-sea nodules and crusts. The depositions of...
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New Germ Busters Outwit Antibiotic-Resistant Bacteria
By Erin Biba
From http://www.wired.com/medtech/health/magazine/17-06/st_germbusters
Infectious bacteria have evolved through the loopholes in almost every drug we've created, thanks to our own misuse and overuse. But we may yet outmaneuver them. Researchers are testing new bug-killers that bypass the molecular pathways used by...
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Microbial communities in industrial environment.
Maukonen J, Saarela M. Curr Opin Microbiol. 2009 May 14. [Epub ahead of print]
VTT Technical Research Centre of Finland, P.O. Box 1000, FI-02044 VTT, Finland.
There is a wealth of techniques that can and have been used for the characterization of industrial microbial communities. Recently, especially PCR-based methods have been...
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Methods for unveiling cryptic microbial partnerships in nature.
Orphan VJ. Curr Opin Microbiol. 2009 May 15. [Epub ahead of print]
Division of Geological and Planetary Sciences, California Institute of Technology, United States.
Syntrophy and mutualism play a central role in carbon and nutrient cycling by microorganisms. Yet our ability to recognize these partnerships in nature or...
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Exosomes - vesicular carriers for intercellular communication.
Simons M, Raposo G. Curr Opin Cell Biol. 2009 May 11. [Epub ahead of print]
Max-Planck-Institute for Experimental Medicine, Hermann-Rein-Str. 3, Göttingen, Germany; Department of Neurology, Robert-Koch-Str. 40, University of Göttingen, Göttingen, Germany.
Cells release different types of vesicular carriers...
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Peptide trafficking and translocation across membranes in cellular signaling and self-defense strategies. Abele R, Tampé R. Curr Opin Cell Biol. 2009 May 12.
Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Max-von-Laue Str. 9, D-60438 Frankfurt a.M., Germany.
Cells are metastable per se and a fine-tuned balance of de novo protein synthesis and degradation...
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Recruitment of condensin to replication origin regions by ParB/SpoOJ promotes chromosome segregation in B. subtilis.
Gruber S, Errington J. Cell. 2009 May 15;137(4):685-96.
Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Framlington Place, Newcastle Upon Tyne, NE2 4HH, UK.
Proper segregation of DNA replication products is...
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Recruitment of SMC by ParB-parS organizes the origin region and promotes efficient chromosome segregation.
Sullivan NL, Marquis KA, Rudner DZ. Cell. 2009 May 15;137(4):697-707. Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.
Organization and segregation of replicated chromosomes are essential processes during cell...
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